When a company with a market cap over $6 billion operates in one of the most mature and complicated industries beats on earnings per share, investors should take notice; when a company beats the market consensus by 300%, investors should move.

Athenahealth, Inc (NASDAQ:ATH) went into their Thursday night conference call with loud murmurs of a pending beat, but even the optimistic investor was shocked when they reported an earnings per shares of $0.28. The consensus was $0.07. The market response for this great news was an 8.44% stock increase just in the next day alone. Though, do they have any upside left in them?

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